Research Focus Area(s)
- Cerebral Palsy Research Scoliosis Spinal Cord Injury
Languages
English, Mandarin Chinese
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Dr. Chen received his PhD degree in Biomedical Engineering. During the PhD program, Dr. Chen developed several rehabilitation medical device prototypes, including a patented hand function rehabilitation training robot system. After receiving his PhD, he joined the Brain Plasticity Laboratory at the University of Minnesota as a Postdoctoral Associate. During his Postdoc period, he received extensive neuromodulation related research trainings and participated in the NIH R21 and R01 studies investigating the pathophysioloty of focal hand dystonia and spasmodic dysphonia. After his Postdoc training, Dr. Chen took a position to establish the Non-invasive Neuromodulation Laboratory at the University of Minnesota serving as the Scientist, and the Manager of the Lab. During this period, he established the lab which significantly facilitated the neuromodulation related research at UMN. He was also heavily involved in several neuromdoulation research at UMN. After the mission of his role at the neuromodulation lab was accomplished, he took his current postion at Gillette Children's seving as a Clinical Scientist in the Neuroscience Reserach Program where his is implementing his neuromodulation knowledge and techniques together with other treatmens to form novel intervention paradigms for children with cerebral palsy, spinal cord injuries or other neurological conditions.
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I combine neuromodulation techniques, including transcranial magnetic stimulation, transcranial direct current stimulation, paired associative stimulation and electrical stimulation, with other techniques, including neuroimaging, electromyogram, electroencephalogram, neuronavigation and robotic system, to form multimodal intervention for neurological conditions. This involves multidisciplinary background knowledge and collaborations with experts from different fields. Combining with existing conventional therapies, the interventions have the potential to form novel treatment protocols or innovative medical devices to benefit patient populations.
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- Graduate Degree:
- Zhejiang University, PhD in Biomedical Engineering
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- AACPDM member
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Chen, M., Summers, R. L. S., Prudente, C. N., Goding, G. S., Samargia-Grivette, S., Ludlow, C. L., & Kimberley, T. J. (2020). Transcranial magnetic stimulation and functional magnet resonance imaging evaluation of adductor spasmodic dysphonia during phonation., Brain Stimulation 13(3), 908–915.
Chen, M., Summers, R. L., Goding, G. S., Samargia, S., Ludlow, C. L., Prudente, C. N., & Kimberley, T. J. (2017). Evaluation of the Cortical Silent Period of the Laryngeal Motor Cortex in Healthy Individuals. Frontiers in neuroscience, 11, 88.
Chen, M., Lixandrão, M. C., Prudente, C. N., Summers, R. L. S., & Kimberley, T. J. (2018). Short Interval Intracortical Inhibition Responses to Low-Frequency Repetitive Transcranial Magnetic Stimulation Under Multiple Interstimulus Intervals and Conditioning Intensities. Neuromodulation : journal of the International Neuromodulation Society, 21(4), 368–375.
Find a list of Dr. Chen's publications here.
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Mo Chen, PhD, Research Areas of Interest
Combining neuromodulation, neuroimaging, rehabilitation engineering and other innovative technologies to improve quality of life of children with CP, Scoliosis, SCI and other neurological conditions.
Investigating the mechanism and effectiveness of non-invasive neuromodulation techniques, including transcranial magnetic stimulation (TMS), repetitive TMS (rTMS), transcranial current stimulation (tDCS, tACS, tRNS, tPCS), paired associative stimulation (PAS).. etc. Combining neuroimaging (functional magnetic resonance image, fMRI, resting-state fMRI, and diffusion tensor imaging, DTI) and neuromodulation techniques to investigate pathophysiology of neurological and psychiatric disorders, e.g. Focal Dystonia, Spasmodic Dysphonia, and Stroke. Using neuromodulation techniques as a treatment to neurological or psychiatric disorders. Closed-loop neuromodulation technique development, such as real-time phase-locked EEG-TMS/rTMS, functional/structure imaging neuronavigation guided TMS/rTMS and tDCS.
